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RCSB PDB - 6BS1: Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion
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DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? | PLOS Genetics
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Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites | PNAS
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Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? | PLOS Genetics
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DNA polymerase η promotes nonhomologous end joining upon etoposide exposure dependent on the scaffolding protein Kap1 - Journal of Biological Chemistry
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DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
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Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance | Science Signaling
Science Signaling - The DNA polymerase Pol-kappa endows tumor cells with resistance to the BRAF inhibitor vemurafenib without increasing mutagenesis, according to new research from the White lab. https://fcld.ly/5jaum2s Credit: K. Temprine
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms | ACS Chemical Biology
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